To absorb the medicine you take, the molecules inside the drug must not have an electrical charge, which allows them to pass through our membrane. pKa is a value that indicates the acidity and basicity in a balanced aqueous solution. It’s similar to cooking, you can put salt into your food as much as you want, but at a certain point you overshoot the ideal amount of salt, and the food becomes too salty to be enjoyable.īefore we can understand the role of the pKa in drug overdosing, we need to understand the concept of pKa and its effects on absorption and excretion. Why? The human body can only tolerate a certain amount of drugs, so the accumulation of medicine could start to harm and disturb your body’s systems. ![]() ![]() In some cases, people might take an extra pill to achieve wellness sooner, but that extra pill might be harmful more than helpful. It’s natural for people to prefer being healthy over being sick, which prompts them to be responsible with their medication.
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